Nordic Bioscience https://www.nordicbioscience.com/ Tue, 04 Nov 2025 12:24:29 +0000 en-US hourly 1 https://wordpress.org/?v=6.8.3 https://www.nordicbioscience.com/wp-content/uploads/2025/02/cropped-logo_nordic_bioscience_new_shape-32x32.png Nordic Bioscience https://www.nordicbioscience.com/ 32 32 Endotrophin & PRO-C6 | Webinar https://www.nordicbioscience.com/blog/endotrophin-pro-c6-webinar/ https://www.nordicbioscience.com/blog/endotrophin-pro-c6-webinar/#respond Tue, 04 Nov 2025 12:24:10 +0000 https://www.nordicbioscience.com/?p=37393 Collagen VI Biomarkers for Mechanism, Prognosis, and Drug Development Overview Type VI collagen sits at the intersection of fibroblast activation, fibrogenesis, and wound healing. Two assays quantify distinct aspects of this axis: Together, these assays provide complementary insights: PRO-C6 reflects total collagen VI formation, while Endotrophin isolates the signaling activity of Endotrophin, offering a more […]

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]]> https://www.nordicbioscience.com/blog/endotrophin-pro-c6-webinar/feed/ 0 Webinar | Breaking down the Matrix: Autoimmunity – Nordic Bioscience https://www.nordicbioscience.com/blog/webinar-breaking-down-the-matrix-autoimmunity-nordic-bioscience/ https://www.nordicbioscience.com/blog/webinar-breaking-down-the-matrix-autoimmunity-nordic-bioscience/#respond Fri, 10 Oct 2025 13:14:09 +0000 https://www.nordicbioscience.com/?p=36110 Breaking down the Matrix: The Interplay Between Fibrosis, Inflammation, and Autoimmunity Watch our latest dermatology webinar “Breaking down the Matrix: The Interplay Between Fibrosis, Inflammation, and Autoimmunity”, to learn more about the role of the ECM in the pathogenesis of autoimmune conditions affecting both skin and joints, with a focus on systemic sclerosis and lupus. […]

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]]> https://www.nordicbioscience.com/blog/webinar-breaking-down-the-matrix-autoimmunity-nordic-bioscience/feed/ 0 The PRO-C3 Story | Webinar https://www.nordicbioscience.com/blog/the-pro-c3-story-webinar/ https://www.nordicbioscience.com/blog/the-pro-c3-story-webinar/#respond Tue, 23 Sep 2025 08:35:51 +0000 https://www.nordicbioscience.com/?p=34530 Fibroblast Activity is Highly Prognostic for Outcome in Over 50 Chronic Diseases Overview Fibroblast activity is a major cause of 35% of deaths in the Western world. Fibroblasts are key drivers of outcome in solid tumors as well as in fibrosis of the liver, lung, kidney, intestine, skin, and in heart failure. To alter the trajectory of organ failure and patient outcomes, we […]

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]]> https://www.nordicbioscience.com/blog/the-pro-c3-story-webinar/feed/ 0 From pTau217 to α-Synuclein: New Biomarkers Driving Neurodegeneration and Neuroinflammation Research https://www.nordicbioscience.com/blog/biomarkers-of-neuroinflammation-and-neurodegeneration/ https://www.nordicbioscience.com/blog/biomarkers-of-neuroinflammation-and-neurodegeneration/#respond Tue, 08 Jul 2025 08:50:51 +0000 https://www.nordicbioscience.com/?p=13639 Alzheimer’s Disease, Multiple Sclerosis and Parkinson’s Disease are neurological disorders with devastating consequences for those affected and their families. These diseases are characterized by a lack of biomarkers specifically tracking disease progression and the effect of potential disease modifying therapies, leading to inadequate treatment possibilities and patient care. In our recent webinar, “The Brain’s Breakdown: […]

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]]> https://www.nordicbioscience.com/blog/biomarkers-of-neuroinflammation-and-neurodegeneration/feed/ 0 Canstatin Is Associated with Mortality Risk in Advanced Atherosclerosis https://www.nordicbioscience.com/blog/canstatin-is-associated-with-mortality-risk-in-advanced-atherosclerosis/ https://www.nordicbioscience.com/blog/canstatin-is-associated-with-mortality-risk-in-advanced-atherosclerosis/#respond Tue, 01 Jul 2025 12:34:02 +0000 https://www.nordicbioscience.com/?p=12653 Canstatin, a type IV collagen fragment, is associated with risk of cardiovascular and all-cause mortality in patients with advanced atherosclerosis Introduction Atherosclerosis, a common underlying cause of cardiovascular disease, is defined by the formation ofplaques in the arterial walls. Changes in the ECM composition impact the risk for plaque rupture, which may cause acute complications […]

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]]> https://www.nordicbioscience.com/blog/canstatin-is-associated-with-mortality-risk-in-advanced-atherosclerosis/feed/ 0 The Brain’s Breakdown: Biomarkers and ECM in Neuroinflammation and Neurodegeneration https://www.nordicbioscience.com/blog/the-brains-breakdown-biomarkers-and-ecm-in-neuroinflammation-and-neurodegeneration/ https://www.nordicbioscience.com/blog/the-brains-breakdown-biomarkers-and-ecm-in-neuroinflammation-and-neurodegeneration/#respond Fri, 27 Jun 2025 07:38:55 +0000 https://www.nordicbioscience.com/?p=9731 In this webinar we uncovered how the brain’s extracellular matrix (ECM) and emerging biomarkers are reshaping our understanding of neuroinflammation and neurodegeneration, with a focus on their role in disease mechanisms, diagnosis, and therapeutic innovation. The brain is more than just neurons; it is a complex, finely tuned environment shaped by the extracellular matrix (ECM) […]

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]]> https://www.nordicbioscience.com/blog/the-brains-breakdown-biomarkers-and-ecm-in-neuroinflammation-and-neurodegeneration/feed/ 0 Investigating Type IV Collagen Biomarkers in Multiple Sclerosis https://www.nordicbioscience.com/blog/investigating-type-iv-collagen-biomarkers-in-multiple-sclerosis/ https://www.nordicbioscience.com/blog/investigating-type-iv-collagen-biomarkers-in-multiple-sclerosis/#respond Thu, 19 Jun 2025 07:05:00 +0000 https://www.nordicbioscience.com/?p=19375 Multiple sclerosis (MS) is characterized as an inflammatory neurodegenerative disease in the central nervous system (CNS), presenting with significant inter- and intra individual heterogeneity. The pathological hallmarks of active MS lesions are blood brain barrier (BBB) disruption, inflammation, and demyelination with axonal damage. Blood-based biomarkers reflecting tissue changes in immunology and/or neurobiology may reflect MS […]

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]]> https://www.nordicbioscience.com/blog/investigating-type-iv-collagen-biomarkers-in-multiple-sclerosis/feed/ 0 Collagen Type I Degradation Biomarkers Are Associated with Risk of Mortality After STEMI https://www.nordicbioscience.com/blog/collagen-type-i-degradation-biomarkers-are-associated-with-risk-of-mortality-after-stemi/ https://www.nordicbioscience.com/blog/collagen-type-i-degradation-biomarkers-are-associated-with-risk-of-mortality-after-stemi/#respond Thu, 12 Jun 2025 08:44:00 +0000 https://www.nordicbioscience.com/?p=13643 Collagen type I degradation biomarkers are associated with risk of mortality after ST-elevatedmyocardial infarction. Introduction Following ST-elevation myocardial infarction (STEMI), there is acute degradation of type I collagen (COL1), the primary structural protein of the myocardium. This process reflects extensive extracellular matrix remodeling, which may contribute to cardiac tissue destabilization and elevate the risk of […]

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]]> https://www.nordicbioscience.com/blog/collagen-type-i-degradation-biomarkers-are-associated-with-risk-of-mortality-after-stemi/feed/ 0 ACR70 Response and Its Dependence on Deep Tissue Efficacy https://www.nordicbioscience.com/blog/acr70-response-and-its-dependence-on-deep-tissue-efficacy/ https://www.nordicbioscience.com/blog/acr70-response-and-its-dependence-on-deep-tissue-efficacy/#respond Wed, 11 Jun 2025 08:57:00 +0000 https://www.nordicbioscience.com/?p=14386 Introduction Over the past decade, drugs developed for rheumatoid arthritis (RA) have been approved based on an ACR20 response rate of 60%. There is an increasing need for new RA drugs to achieve an ACR100 response in a significant portion of patients. Achieving ACR100 can profoundly improve patients’ quality of life by reducing pain, enhancing […]

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]]> https://www.nordicbioscience.com/blog/acr70-response-and-its-dependence-on-deep-tissue-efficacy/feed/ 0 Serological Extracellular Matrix Fragments May Serve as Early Kidney Damage Biomarkers https://www.nordicbioscience.com/blog/serological-extracellular-matrix-fragments-may-serve-as-early-kidney-damage-biomarkers/ https://www.nordicbioscience.com/blog/serological-extracellular-matrix-fragments-may-serve-as-early-kidney-damage-biomarkers/#respond Wed, 04 Jun 2025 10:01:00 +0000 https://www.nordicbioscience.com/?p=13649 Serological extracellular matrix fragments may serve as early kidney damage biomarkers in children with defects in Alport genes Introduction Alport syndrome is a genetic disorder caused by variants in COL4A3, COL4A4, or COL4A5, which encode type IV collagen. The α3.α4.α5(IV) collagen network is a critical structural component of the glomerular and tubular basement membranes within […]

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